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  1. NTU Theses and Dissertations Repository
  2. 工學院
  3. 醫學工程學研究所
請用此 Handle URI 來引用此文件: http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/15936
完整後設資料紀錄
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dc.contributor.advisor林啟萬(Chii-Wann Lin)
dc.contributor.authorYuan-Kai Rayen
dc.contributor.author雷元凱zh_TW
dc.date.accessioned2021-06-07T17:55:51Z-
dc.date.copyright2012-08-19
dc.date.issued2012
dc.date.submitted2012-08-15
dc.identifier.citation[1] Cornish B.H., Chapman M., & Hirst C., “Early diagnosis of lymphoedema using multiple frequency bioimpedance,” Lymphology,vol. 34, pp. 2-11,2001.
[2] Ward, L.C., Bunce, I.H.,& Cornish, B.H., “Multi-frequency bioelectrical impedance augments the diagnosis and management of lymphoedema in post-mastectomy patients,” Eur. J. Clin. Invest, Vol. 22, pp.751-754,1992.
[3] Cornish, B.H., Mirolo, B., & Bunce, I.H.,” Sweep frequency bioelectrical impedance analysis for the diagnosis of lymphedema,” Breast Cancer Research Treatment, vol.38, pp.169-176, 1995.
[4] Ward, L.C., Bunce, I.H., & Cornish, B.H., “Bioelectrical impedance for monitoring the efficacy of lymphoedema treatment programmes,” Breast Cancer Research and Treatment, vol. 38, pp.169-176, 1996.
[5] Piccoli, Antonio., Pastori, Giordano., Codognotto, Marta et. al.,”Equivalence of information from single frequency v. bioimpedance spectroscopy in bodybuilders,” British Journal of Nutrition, vol. 97, pp. 182-192, 2007.
[6] Silva, A. M, Heymsfield, S. B, Gallagher, & D., Albu, J., “Evaluation of between-methods agreement of extracellular water measurements in adults and children,” Am. J. Clin. Nutr,vol. 88,pp. 315-323, 2008.
[7] Seoane, Fernando., Ferreira, Javier,. Sanchez, Juan Jose., & Bragos, Ramon.,” Analog Front-End Enables Electrical Impedance Spectroscopy System On-Chip for Biomedical Applications,” Physiological Measurement, vol. 29, pp. 267-278, 2007.
[8] Tao Dai., & Andy Adler., “Blood Characterization from Pulsatile” Bioimpedance Spectroscopy. 30th Conf Canadian Medical and Biomedical Engineering Society Toronto, Ontario, pp. 18-20, 2007
[9] Tao Dai, & Andy Adler.,” In Vivo Blood Characterization From Bioimpedance Spectroscopy of Blood Pooling,” In Press: IEEE Trans. Instrumentation and Measurement, 2008
[10] Warren, A., Janz, B., Sumner, A., & Borud, L.,” The Use of Bioimpedance Analysis to Evaluate Lymphedema,” Analysis of Plastic Surgery,vol.58(5), pp 541-543, 2007.
[11] Ward, L. C., & Cornish, B. H.,” Multiple frequency bioelectrical impedance analysis. How many frequencies to use?” Medical Physics, Diagnostic methods,2004
[12] Kissin MW., Querci Della Rovere G., & Easton D., “ The risk of lymphedema following the treatment of breast cancer,” Br. J. Surg.,vol.73, pp.580 – 4, 1986.
[13] J. Sitzia J., Stanton AW., & Badger C., “A review of outcome indicators in the treatment of chronic limb edema,” Clin Rehabil, vol.11,pp.181–91. 1997
[14] Foldi E., Foldi M., & Clodius.,” The lymphedema chaos: alancet,” Ann Plast Surg, vol.22, 505–15. 1989.
[15] Bunce IH., Mirolo BR., & Hennessy JM., “Post mastectomy lymphoedema treatment and measurement,” Med J Aust,vol 8,pp.161-125, 1994
[16] Mortimer PS.,” Investigation and management of lymphedema,” Vasc Med Rev,vol.1,pp. 1–20, 19903
[17] Kaulesar Sukal DMKS., den Hoed PT.,& Johannes EJ., “Direct and indirect methods for the quantification of leg volume: comparison between water displacement volumetry, the dish model method and the frustum sign model method, using the correlation coefficient and the limits of agreement,” J. Biomed. Eng.,vol 15.pp.477– 80, 1993.
[18] Clodius L., Deak L., & Piller NB.,” A new instrument for the evaluation of tissue tonicity in lymphedema” Lymphology, vol.9, pp.1–5. 1976
[19] Piller NB., & Clodius L., “The use of a tissue tonometer as a diagnostic aid in extremity lymphoedema: a determination of its conservative treatment with benzo-pyrones,” Lymphology,vol.9, pp.127–32, 1976.
[20] Duwell S., Hagspiel KD., & Zuber J.,” Swollen lower extremity: role of MR imaging,” Radiology,vol.184, pp.227–31, 1992.
[21] Stewart G., Hurst PAG., & Lea Thomas M.,” CAT scanning inthe management of the lymphoedematous limb,” Immunol Haematol Res,vol.2,pp.241–3, 1983
[22] Flippetti M., Santoro E., & Graziano F., “Modern therapeutic approaches to post mastectomy brachial lymphedema,”Microsurgery, 1994, vol.15,pp.604 –10.
[23] Campisi C., Boccardo F., & Tacchella M., “Reconstructive micro surgery of lymph vessels,” Microsurgery, vol.16, pp.161– 6, 1995.
[24] Grabois M., “Postmastectomy lymphedema.State of the art review,” Phys Med Rehabil Rev, vol.8, pp.267–77, 1994
[25] Foldi E., Foldi M., & Clodius L.,” The lymphedema chaos: alancet,” Ann Plast Surg, vol.22, pp.505–15, 1989.
[26] Passik S., Newmann M., Brennan M., & Holland J., “Psychiatric consultation for women undergoing rehabilitation for upper- extremity lymphedema following breast cancer treatment”J. Pain Sympt. Manage, vol.8(4), pp.226 –33, 1993.
[27] Passik S., Newmann M., Brennan M., & Tunkel R.,” Predictors of psychiatric distress in patients with upper extremity lymphedema,” Psycho-Oncology, vol.4, pp.255–63, 1995.
[28] Bunce IH., Mirolo BR., Hennessy JM., Ward LC., Jones LC., et al., “Post-mastectomy lymphoedema treatment and measurement,” Med. J,vol161(2), pp.125– 8, 1994.
[29] Klein MJ., Alexander MA., Wright JM., Redmond CK., LaGasseAA., et al.,” Treatment of adult lower extremity lymphedema withthe Wright Linear pump: statistical analysis of a clinical trial,” Arch PM&R, vol.69, 202–6, 1988.
[30] Tsai W.S., Wu C.C.,Lin S.H.,Chu P.,& Wu S.C. et al., “BIA for evaluating dry weight,” Acta Nephrologica,Vol.16, pp.3, 2002.
dc.identifier.urihttp://tdr.lib.ntu.edu.tw/jspui/handle/123456789/15936-
dc.description.abstract本研究在於發展出一可攜式淋巴水腫評估裝置,目標是開發出體積小、重量輕、容易操作的感測器。為了方便使用,感測器使用阻抗量測,阻抗量測具有量測迅速、非侵入性,對細微變化靈敏的優點,較過去使用的周長量測法及體積量測法更為科學。並將以 LabVIEW設計一簡易電腦視窗接收介面,資料傳入資料庫後未來可作更深入的分析。淋巴水腫評估裝置由電腦控制,可由電腦決定掃描間隔頻率及起始頻率。感測器目前設定應用為淋巴水腫之評估,讀取外細胞液的阻抗,阻抗的大小會與外細胞液的累積量成反比,因此可以評估淋巴水腫的嚴重程度。本研究將以模擬電路校正系統對電阻及電抗所產生的偏差。並使用電極對豬肉進行量測,來模擬在使用在人身上所可能產生的各種現象,並加以改進。並期望最終能使用在人身上。zh_TW
dc.description.abstractThis research is to develop a portable biochemical lymphedema evaluation device which should be lightweight, compact size, ease of use. For convenient use. device use bioimpedance as reference. The bioimpedance measurement have characteristic that fast measurement、none invasion、 sensitive and more scientific than past ways like circumferential measures and volumetric measures. A user interface, developed under the LabVIEW, is developed for data collection, could efficiently send back to the database for further analysis.
Device currently used for lymphedema evaluation, use sine wave measure ECW impedance. The impedance will inverse propotion to ECW, thus we can evaluation how bad lymphedema become. This research will compare data between idea data and measurement data for device calibration, and use pork as experiment target for further understanding device performance on real human
The results, obtained from pork show that the output impedance of this device can indicator the water amount variation. The finished prototype is very compact, about the same size as a paw of a human being, and is suitable for portable use.
en
dc.description.provenanceMade available in DSpace on 2021-06-07T17:55:51Z (GMT). No. of bitstreams: 1
ntu-101-R96548007-1.pdf: 1977041 bytes, checksum: 11e4150017a41df7f40eeef6996fee6c (MD5)
Previous issue date: 2012
en
dc.description.tableofcontents目錄
目錄
中文摘要 i
ABSTRACT ii
致謝 iii
目錄 iv
圖目錄 vi
表目錄 ix
第ㄧ章 緒論 1
1.1背景 1
1.2動機 4
1.3 文獻回顧 6
1.4 理論基礎 9
1.4.1生物阻抗分析 9
1.4.2 淋巴水腫評估機制 12
第二章 系統架構 16
2.1系統架構要述 16
2.2 硬體要述 17
2.2.1 USB控制電路 18
2.2.2 AD5933核心電路 20
2.2.3 雜訊處理電路 25
第三章 程式部分 29
3.1 軟體要述 29
3.1.1 系統程式流程 30
3.2 AD5933與USB控制器間的傳輸 32
3.3 人機介面程式 34
3.3.1使用者視窗 34
3.3.2 軟體校正 35
第四章 實驗方法與結果 37
4.1校正程序 37
4.2 以已知電阻校正 38
4.3 以已知電容校正 40
4.4生物組織實驗 43
4.4.1觀察水分含量程度不同組織的阻抗變化 43
4.4.2 整塊豬肉注射水分 49
4.5 人體量測 53
第五章 討論 55
第六章 結論與未來展望 59
參考文獻 60
附錄A 量測資料 63
附錄B 人體建模 66
dc.language.isozh-TW
dc.subject阻抗量測儀zh_TW
dc.subject淋巴水腫評估zh_TW
dc.subject虛擬儀表zh_TW
dc.subject電阻抗zh_TW
dc.subjectbioimpedanceen
dc.subjectLyphmedama evaluationen
dc.subjectLabVIEWen
dc.title應用於淋巴腫脹評估之生醫阻抗量測系統開發zh_TW
dc.titleThe development of bio-impedance measurement system used on lymphedema evaluationen
dc.typeThesis
dc.date.schoolyear100-2
dc.description.degree碩士
dc.contributor.oralexamcommittee邱南福(Nan-Fu Chiu),李舒昇(Shu-Sheng Lee)
dc.subject.keyword淋巴水腫評估,虛擬儀表,電阻抗,阻抗量測儀,zh_TW
dc.subject.keywordLyphmedama evaluation,LabVIEW,bioimpedance,en
dc.relation.page69
dc.rights.note未授權
dc.date.accepted2012-08-15
dc.contributor.author-college工學院zh_TW
dc.contributor.author-dept醫學工程學研究所zh_TW
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