請用此 Handle URI 來引用此文件：
http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/15751完整後設資料紀錄
| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 闕玲玲(Ling-Ling Chueh) | |
| dc.contributor.author | Min-Hsiu Wang | en |
| dc.contributor.author | 王敏琇 | zh_TW |
| dc.date.accessioned | 2021-06-07T17:51:21Z | - |
| dc.date.copyright | 2012-10-12 | |
| dc.date.issued | 2012 | |
| dc.date.submitted | 2012-09-26 | |
| dc.identifier.citation | 57
參考文獻 Addie, D.D., 2004, Feline coronavirus--that enigmatic little critter. Vet J 167, 5-6. Addie, D.D., Jarrett, O., 1992, A study of naturally occurring feline coronavirus infections in kittens. Vet Rec 130, 133-137. Addie, D.D., Schaap, I.A., Nicolson, L., Jarrett, O., 2003, Persistence and transmission of natural type I feline coronavirus infection. J Gen Virol 84, 2735-2744. Addie, D.D., Toth, S., Murray, G.D., Jarrett, O., 1995, Risk of feline infectious peritonitis in cats naturally infected with feline coronavirus. Am J Vet Res 56, 429-434. Adombi, C.M., Lelenta, M., Lamien, C.E., Shamaki, D., Koffi, Y.M., Traore, A., Silber, R., Couacy-Hymann, E., Bodjo, S.C., Djaman, J.A., Luckins, A.G., Diallo, A., 2011, Monkey CV1 cell line expressing the sheep-goat SLAM protein: a highly sensitive cell line for the isolation of peste des petits ruminants virus from pathological specimens. J Virol Methods 173, 306-313. Alazawy Amer, Arshad Siti-Suri, Hair-Bejo Mohd, Omar Abdul-Rahman, Tengku-Ibrahim, Tengku-Azmi, Bande Faruku, Ajwad, A., 2012, Molecular and pathological identification of feline coronavirus type I. African Journal of Biotechnology Vol., 10451-10461. Alvarez, C.P., Lasala, F., Carrillo, J., Muniz, O., Corbi, A.L., Delgado, R., 2002, C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in trans. J Virol 76, 6841-6844. An, D.J., Jeoung, H.Y., Jeong, W., Park, J.Y., Lee, M.H., Park, B.K., 2011, Prevalence of Korean cats with natural feline coronavirus infections. Virol J 8, 455.58 Bell, E.T., Toribio, J.A., White, J.D., Malik, R., Norris, J.M., 2006, Seroprevalence study of feline coronavirus in owned and feral cats in Sydney, Australia. Aust Vet J 84, 74-81. Benetka, V., Kubber-Heiss, A., Kolodziejek, J., Nowotny, N., Hofmann-Parisot, M., Mostl, K., 2004, Prevalence of feline coronavirus types I and II in cats with histopathologically verified feline infectious peritonitis. Vet Microbiol 99, 31-42. Black, J.W., 1980, Recovery and in vitro cultivation of a coronavirus from laboratory-induced cases of feline infectious peritonitis (FIP). Vet Med Small Anim Clin 75, 811-814. Brian, D.A., Baric, R.S., 2005, Coronavirus genome structure and replication. Curr Top Microbiol Immunol 287, 1-30. Can-Sahna, K., Soydal Ataseven, V., Pinar, D., Oguzoglu, T.C., 2007, The detection of feline coronaviruses in blood samples from cats by mRNA RT-PCR. J Feline Med Surg 9, 369-372. Cavanagh, D., 1997, Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch Virol 142, 629-633. Chang, H.W., de Groot, R.J., Egberink, H.F., Rottier, P.J., 2010, Feline infectious peritonitis: insights into feline coronavirus pathobiogenesis and epidemiology based on genetic analysis of the viral 3c gene. J Gen Virol 91, 415-420. Cornelissen, E., Dewerchin, H.L., Van Hamme, E., Nauwynck, H.J., 2007, Absence of surface expression of feline infectious peritonitis virus (FIPV) antigens on infected cells isolated from cats with FIP. Vet Microbiol 121, 131-137. Cotter, S.M., Gilmore, C.E., Rollins, C., 1973, Multiple cases of feline leukemia and 59 feline infectious peritonitis in a household. J Am Vet Med Assoc 162, 1054-1058. Cserzo, M., Wallin, E., Simon, I., von Heijne, G., Elofsson, A., 1997, Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. Protein Eng 10, 673-676. De Groot, R.J., Andeweg, A.C., Horzinek, M.C., Spaan, W.J., 1988, Sequence analysis of the 3'-end of the feline coronavirus FIPV 79-1146 genome: comparison with the genome of porcine coronavirus TGEV reveals large insertions. Virology 167, 370-376. Duarte, A., Veiga, I., Tavares, L., 2009, Genetic diversity and phylogenetic analysis of Feline Coronavirus sequences from Portugal. Vet Microbiol 138, 163-168. Dye, C., Siddell, S.G., 2007, Genomic RNA sequence of feline coronavirus strain FCoV C1Je. J Feline Med Surg 9, 202-213. Dye, C., Temperton, N., Siddell, S.G., 2007, Type I feline coronavirus spike glycoprotein fails to recognize aminopeptidase N as a functional receptor on feline cell lines. J Gen Virol 88, 1753-1760. Evermann, J.F., Baumgartener, L., Ott, R.L., Davis, E.V., McKeirnan, A.J., 1981, Characterization of a feline infectious peritonitis virus isolate. Vet Pathol 18, 256-265. Evermann, J.F., Heeney, J.L., McKeirnan, A.J., O'Brien, S.J., 1989, Comparative features of a coronavirus isolated from a cheetah with feline infectious peritonitis. Virus Res 13, 15-27. Foley, J.E., Lapointe, J.M., Koblik, P., Poland, A., Pedersen, N.C., 1998, Diagnostic features of clinical neurologic feline infectious peritonitis. J Vet Intern Med 12, 60 415-423. Foley, J.E., Poland, A., Carlson, J., Pedersen, N.C., 1997, Risk factors for feline infectious peritonitis among cats in multiple-cat environments with endemic feline enteric coronavirus. J Am Vet Med Assoc 210, 1313-1318. Geijtenbeek, T.B., Torensma, R., van Vliet, S.J., van Duijnhoven, G.C., Adema, G.J., van Kooyk, Y., Figdor, C.G., 2000, Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 100, 575-585. Geijtenbeek, T.B., van Duijnhoven, G.C., van Vliet, S.J., Krieger, E., Vriend, G., Figdor, C.G., van Kooyk, Y., 2002, Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1. J Biol Chem 277, 11314-11320. Gorbalenya, A.E., Enjuanes, L., Ziebuhr, J., Snijder, E.J., 2006, Nidovirales: evolving the largest RNA virus genome. Virus Res 117, 17-37. Haijema, B.J., Volders, H., Rottier, P.J., 2004, Live, attenuated coronavirus vaccines through the directed deletion of group-specific genes provide protection against feline infectious peritonitis. J Virol 78, 3863-3871. Hartmann, K., 2005, Feline infectious peritonitis. Vet Clin North Am Small Anim Pract 35, 39-79, vi. Hartmann, K., Binder, C., Hirschberger, J., Cole, D., Reinacher, M., Schroo, S., Frost, J., Egberink, H., Lutz, H., Hermanns, W., 2003, Comparison of different tests to diagnose feline infectious peritonitis. J Vet Intern Med 17, 781-790. Herrewegh, A.A., de Groot, R.J., Cepica, A., Egberink, H.F., Horzinek, M.C., Rottier, P.J., 1995a, Detection of feline coronavirus RNA in feces, tissues, and body 61 fluids of naturally infected cats by reverse transcriptase PCR. J Clin Microbiol 33, 684-689. Herrewegh, A.A., Mahler, M., Hedrich, H.J., Haagmans, B.L., Egberink, H.F., Horzinek, M.C., Rottier, P.J., de Groot, R.J., 1997, Persistence and evolution of feline coronavirus in a closed cat-breeding colony. Virology 234, 349-363. Herrewegh, A.A., Smeenk, I., Horzinek, M.C., Rottier, P.J., de Groot, R.J., 1998, Feline coronavirus type II strains 79-1683 and 79-1146 originate from a double recombination between feline coronavirus type I and canine coronavirus. J Virol 72, 4508-4514. Herrewegh, A.A., Vennema, H., Horzinek, M.C., Rottier, P.J., de Groot, R.J., 1995b, The molecular genetics of feline coronaviruses: comparative sequence analysis of the ORF7a/7b transcription unit of different biotypes. Virology 212, 622-631. Hirschberger, J., Hartmann, K., Wilhelm, N., Frost, J., Lutz, H., Kraft, W., 1995, [Clinical symptoms and diagnosis of feline infectious peritonitis]. Tierarztl Prax 23, 92-99. Hohdatsu, T., Izumiya, Y., Yokoyama, Y., Kida, K., Koyama, H., 1998, Differences in virus receptor for type I and type II feline infectious peritonitis virus. Arch Virol 143, 839-850. Hohdatsu, T., Okada, S., Ishizuka, Y., Yamada, H., Koyama, H., 1992, The prevalence of types I and II feline coronavirus infections in cats. J Vet Med Sci 54, 557-562. Hohdatsu, T., Sasamoto, T., Okada, S., Koyama, H., 1991, Antigenic analysis of feline coronaviruses with monoclonal antibodies (MAbs): preparation of MAbs which discriminate between FIPV strain 79-1146 and FECV strain 79-1683. Vet 62 Microbiol 28, 13-24. Hohdatsu, T., Yamato, H., Ohkawa, T., Kaneko, M., Motokawa, K., Kusuhara, H., Kaneshima, T., Arai, S., Koyama, H., 2003, Vaccine efficacy of a cell lysate with recombinant baculovirus-expressed feline infectious peritonitis (FIP) virus nucleocapsid protein against progression of FIP. Vet Microbiol 97, 31-44. Holst, B.S., Englund, L., Palacios, S., Renstrom, L., Berndtsson, L.T., 2006, Prevalence of antibodies against feline coronavirus and Chlamydophila felis in Swedish cats. J Feline Med Surg 8, 207-211. Horzinek, M.C., Lutz, H., Pedersen, N.C., 1982, Antigenic relationships among homologous structural polypeptides of porcine, feline, and canine coronaviruses. Infect Immun 37, 1148-1155. Horzinek, M.C., Osterhaus, A.D., 1979, Feline infectious peritonitis: a worldwide serosurvey. Am J Vet Res 40, 1487-1492. Hsieh, L.E., Lin, C.N., Su, B.L., Jan, T.R., Chen, C.M., Wang, C.H., Lin, D.S., Lin, C.T., Chueh, L.L., 2010, Synergistic antiviral effect of Galanthus nivalis agglutinin and nelfinavir against feline coronavirus. Antiviral Res 88, 25-30. Ishida, T., Shibanai, A., Tanaka, S., Uchida, K., Mochizuki, M., 2004, Use of recombinant feline interferon and glucocorticoid in the treatment of feline infectious peritonitis. J Feline Med Surg 6, 107-109. Jakob, H., 1914, Therapeutsiche, kasuisitische und statistische Mitteilungen aus der Klinik fur kleine Haustiere an der Reichstierarzneischule in Utrecht (Holland), Jahrgang 1912/13. . Z Tiermed Microbiol Immunol 18, 193. Kennedy, M., Boedeker, N., Gibbs, P., Kania, S., 2001, Deletions in the 7a ORF of feline coronavirus associated with an epidemic of feline infectious peritonitis. 63 Vet Microbiol 81, 227-234. Kipar, A., Koehler, K., Bellmann, S., Reinacher, M., 1999, Feline infectious peritonitis presenting as a tumour in the abdominal cavity. Vet Rec 144, 118-122. Kipar, A., May, H., Menger, S., Weber, M., Leukert, W., Reinacher, M., 2005, Morphologic features and development of granulomatous vasculitis in feline infectious peritonitis. Vet Pathol 42, 321-330. Kummrow, M., Meli, M.L., Haessig, M., Goenczi, E., Poland, A., Pedersen, N.C., Hofmann-Lehmann, R., Lutz, H., 2005, Feline coronavirus serotypes 1 and 2: seroprevalence and association with disease in Switzerland. Clin Diagn Lab Immunol 12, 1209-1215. Lai, M.M., 1997, RNA-protein interactions in the regulation of coronavirus RNA replication and transcription. Biol Chem 378, 477-481. Lai, M.M., Cavanagh, D., 1997, The molecular biology of coronaviruses. Adv Virus Res 48. Le Poder, S., 2011, Feline and canine coronaviruses: common genetic and pathobiological features. Adv Virol 2011, 609465. Lin, C.N., Su, B.L., Huang, H.P., Lee, J.J., Hsieh, M.W., Chueh, L.L., 2009a, Field strain feline coronaviruses with small deletions in ORF7b associated with both enteric infection and feline infectious peritonitis. J Feline Med Surg 11, 413-419. Lin, C.N., Su, B.L., Wang, C.H., Hsieh, M.W., Chueh, T.J., Chueh, L.L., 2009b, Genetic diversity and correlation with feline infectious peritonitis of feline coronavirus type I and II: a 5-year study in Taiwan. Vet Microbiol 136, 233-239. Lin, C.N., Su, B.L., Wu, C.W., Heieh, L.N., Chueh, L.L., 2009c, Isolation and 64 identification of a Novel Feline Coronavirus from a Kitten with Naturally Occurring Feline Infectious Peritonitis in Taiwan. Taiwan Vet. J 35, 145-152. Lozach, P.Y., Lortat-Jacob, H., de Lacroix de Lavalette, A., Staropoli, I., Foung, S., Amara, A., Houles, C., Fieschi, F., Schwartz, O., Virelizier, J.L., Arenzana-Seisdedos, F., Altmeyer, R., 2003, DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2. J Biol Chem 278, 20358-20366. Lutz, H., Lehmann, R., Winkler, G., Kottwitz, B., Dittmer, A., Wolfensberger, C., Arnold, P., 1990, [Feline immunodeficiency virus in Switzerland: clinical aspects and epidemiology in comparison with feline leukemia virus and coronaviruses]. Schweiz Arch Tierheilkd 132, 217-225. Maeda, J., Repass, J.F., Maeda, A., Makino, S., 2001, Membrane topology of coronavirus E protein. Virology 281, 163-169. Marzi, A., Gramberg, T., Simmons, G., Moller, P., Rennekamp, A.J., Krumbiegel, M., Geier, M., Eisemann, J., Turza, N., Saunier, B., Steinkasserer, A., Becker, S., Bates, P., Hofmann, H., Pohlmann, S., 2004, DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus. J Virol 78, 12090-12095. McKeirnan, A.J., Evermann, J.F., Davis, E.V., Ott, R.L., 1987, Comparative properties of feline coronaviruses in vitro. Can J Vet Res 51, 212-216. Mochizuki, M., Mitsutake, Y., Miyanohara, Y., Higashihara, T., Shimizu, T., Hohdatsu, T., 1997, Antigenic and plaque variations of serotype II feline infectious peritonitis coronaviruses. J Vet Med Sci 59, 253-258. Montali, R.J., Strandberg, J.D., 1972, Extraperitoneal lesions in feline infectious 65 peritonitis. Vet Pathol 9, 109-121. Myrrha, L.W., Silva, F.M., Peternelli, E.F., Junior, A.S., Resende, M., de Almeida, M.R., 2011, The paradox of feline coronavirus pathogenesis: a review. Adv Virol 2011, 109849. Nishimura, Y., Goto, Y., Pang, H., Endo, Y., Mizuno, T., Momoi, Y., Watari, T., Tsujimoto, H., Hasegawa, A., 1998, Genetic heterogeneity of env gene of feline immunodeficiency virus obtained from multiple districts in Japan. Virus Res 57, 101-112. O'Reilly, K.J., Fishman, B., Hitchcock, L.M., 1979, Feline infectious peritonitis: isolation of a coronavirus. Vet Rec 104, 348. Paltrinieri, S., Cammarata, M.P., Cammarata, G., Comazzi, S., 1998a, Some aspects of humoral and cellular immunity in naturally occuring feline infectious peritonitis. Vet Immunol Immunopathol 65, 205-220. Paltrinieri, S., Cammarata Parodi, M., Cammarata, G., Mambretti, M., 1998b, Type IV hypersensitivity in the pathogenesis of FIPV-induced lesions. Zentralbl Veterinarmed B 45, 151-159. Pedersen, N.C., 1976, Serologic studies of naturally occurring feline infectious peritonitis. Am J Vet Res 37, 1449-1453. Pedersen, N.C., 1987, Virologic and immunologic aspects of feline infectious peritonitis virus infection. Adv Exp Med Biol 218, 529-550. Pedersen, N.C., 2009, A review of feline infectious peritonitis virus infection: 1963-2008. J Feline Med Surg 11, 225-258. Pedersen, N.C., Allen, C.E., Lyons, L.A., 2008, Pathogenesis of feline enteric coronavirus infection. J Feline Med Surg 10, 529-541.66 Pedersen, N.C., Black, J.W., 1983, Attempted immunization of cats against feline infectious peritonitis, using avirulent live virus or sublethal amounts of virulent virus. Am J Vet Res 44, 229-234. Pedersen, N.C., Black, J.W., Boyle, J.F., Evermann, J.F., McKeirnan, A.J., Ott, R.L., 1984, Pathogenic differences between various feline coronavirus isolates. Adv Exp Med Biol 173, 365-380. Pedersen, N.C., Boyle, J.F., Floyd, K., 1981a, Infection studies in kittens, using feline infectious peritonitis virus propagated in cell culture. Am J Vet Res 42, 363-367. Pedersen, N.C., Boyle, J.F., Floyd, K., Fudge, A., Barker, J., 1981b, An enteric coronavirus infection of cats and its relationship to feline infectious peritonitis. Am J Vet Res 42, 368-377. Pedersen, N.C., Hawkins, K.F., 1995, Mechanisms for persistence of acute and chronic feline calicivirus infections in the face of vaccination. Vet Microbiol 47, 141-156. Pedersen, N.C., Sato, R., Foley, J.E., Poland, A.M., 2004, Common virus infections in cats, before and after being placed in shelters, with emphasis on feline enteric coronavirus. J Feline Med Surg 6, 83-88. Peiris, J.S., Lai, S.T., Poon, L.L., Guan, Y., Yam, L.Y., Lim, W., Nicholls, J., Yee, W.K., Yan, W.W., Cheung, M.T., Cheng, V.C., Chan, K.H., Tsang, D.N., Yung, R.W., Ng, T.K., Yuen, K.Y., 2003, Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 361, 1319-1325. Poland, A.M., Vennema, H., Foley, J.E., Pedersen, N.C., 1996, Two related strains of feline infectious peritonitis virus isolated from immunocompromised cats infected with a feline enteric coronavirus. J Clin Microbiol 34, 3180-3184.67 Pyrc, K., Dijkman, R., Deng, L., Jebbink, M.F., Ross, H.A., Berkhout, B., van der Hoek, L., 2006, Mosaic structure of human coronavirus NL63, one thousand years of evolution. J Mol Biol 364, 964-973. Rappocciolo, G., Jenkins, F.J., Hensler, H.R., Piazza, P., Jais, M., Borowski, L., Watkins, S.C., Rinaldo, C.R., Jr., 2006, DC-SIGN is a receptor for human herpesvirus 8 on dendritic cells and macrophages. J Immunol 176, 1741-1749. Regan, A.D., Ousterout, D.G., Whittaker, G.R., 2010, Feline lectin activity is critical for the cellular entry of feline infectious peritonitis virus. J Virol 84, 7917-7921. Regan, A.D., Whittaker, G.R., 2008, Utilization of DC-SIGN for entry of feline coronaviruses into host cells. J Virol 82, 11992-11996. Reubel, G.H., Ramos, R.A., Hickman, M.A., Rimstad, E., Hoffmann, D.E., Pedersen, N.C., 1993, Detection of active and latent feline herpesvirus 1 infections using the polymerase chain reaction. Arch Virol 132, 409-420. Rohrbach, B.W., Legendre, A.M., Baldwin, C.A., Lein, D.H., Reed, W.M., Wilson, R.B., 2001, Epidemiology of feline infectious peritonitis among cats examined at veterinary medical teaching hospitals. J Am Vet Med Assoc 218, 1111-1115. Rottier, P.J., Nakamura, K., Schellen, P., Volders, H., Haijema, B.J., 2005, Acquisition of macrophage tropism during the pathogenesis of feline infectious peritonitis is determined by mutations in the feline coronavirus spike protein. J Virol 79, 14122-14130. Sawicki, S.G., Sawicki, D.L., 2005, Coronavirus transcription: a perspective. Curr Top Microbiol Immunol 287, 31-55. Seki, F., Ono, N., Yamaguchi, R., Yanagi, Y., 2003, Efficient isolation of wild strains of canine distemper virus in Vero cells expressing canine SLAM (CD150) and their 68 adaptability to marmoset B95a cells. J Virol 77, 9943-9950. Shiba, N., Maeda, K., Kato, H., Mochizuki, M., Iwata, H., 2007, Differentiation of feline coronavirus type I and II infections by virus neutralization test. Vet Microbiol 124, 348-352. Simkins, R.A., Weilnau, P.A., Bias, J., Saif, L.J., 1992, Antigenic variation among transmissible gastroenteritis virus (TGEV) and porcine respiratory coronavirus strains detected with monoclonal antibodies to the S protein of TGEV. Am J Vet Res 53, 1253-1258. Soilleux, E.J., Morris, L.S., Leslie, G., Chehimi, J., Luo, Q., Levroney, E., Trowsdale, J., Montaner, L.J., Doms, R.W., Weissman, D., Coleman, N., Lee, B., 2002, Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro. J Leukoc Biol 71, 445-457. Spaan, W., Cavanagh, D., Horzinek, M.C., 1988, Coronaviruses: structure and genome expression. J Gen Virol 69 ( Pt 12), 2939-2952. Stiles, J., Bienzle, D., Render, J.A., Buyukmihci, N.C., Johnson, E.C., 1999, Use of nested polymerase chain reaction (PCR) for detection of retroviruses from formalin-fixed, paraffin-embedded uveal melanomas in cats. Vet Ophthalmol 2, 113-116. Stiles, J., McDermott, M., Willis, M., Roberts, W., Greene, C., 1997, Comparison of nested polymerase chain reaction, virus isolation, and fluorescent antibody testing for identifying feline herpesvirus in cats with conjunctivitis. Am J Vet Res 58, 804-807. Taharaguchi, S., Soma, T., Hara, M., 2012, Prevalence of Feline Coronavirus Antibodies in Japanese Domestic Cats during the Past Decade. J Vet Med Sci.69 Takano, T., Azuma, N., Satoh, M., Toda, A., Hashida, Y., Satoh, R., Hohdatsu, T., 2009, Neutrophil survival factors (TNF-alpha, GM-CSF, and G-CSF) produced by macrophages in cats infected with feline infectious peritonitis virus contribute to the pathogenesis of granulomatous lesions. Arch Virol 154, 775-781. Takano, T., Hohdatsu, T., Hashida, Y., Kaneko, Y., Tanabe, M., Koyama, H., 2007a, A 'possible' involvement of TNF-alpha in apoptosis induction in peripheral blood lymphocytes of cats with feline infectious peritonitis. Vet Microbiol 119, 121-131. Takano, T., Hohdatsu, T., Toda, A., Tanabe, M., Koyama, H., 2007b, TNF-alpha, produced by feline infectious peritonitis virus (FIPV)-infected macrophages, upregulates expression of type II FIPV receptor feline aminopeptidase N in feline macrophages. Virology 364, 64-72. Tassaneetrithep, B., Burgess, T.H., Granelli-Piperno, A., Trumpfheller, C., Finke, J., Sun, W., Eller, M.A., Pattanapanyasat, K., Sarasombath, S., Birx, D.L., Steinman, R.M., Schlesinger, S., Marovich, M.A., 2003, DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J Exp Med 197, 823-829. Tekes, G., Hofmann-Lehmann, R., Bank-Wolf, B., Maier, R., Thiel, H.J., Thiel, V., 2010, Chimeric feline coronaviruses that encode type II spike protein on type I genetic background display accelerated viral growth and altered receptor usage. J Virol 84, 1326-1333. Timmann, D., Cizinauskas, S., Tomek, A., Doherr, M., Vandevelde, M., Jaggy, A., 2008, Retrospective analysis of seizures associated with feline infectious peritonitis in cats. J Feline Med Surg 10, 9-15.70 Tripet, B., Howard, M.W., Jobling, M., Holmes, R.K., Holmes, K.V., Hodges, R.S., 2004, Structural characterization of the SARS-coronavirus spike S fusion protein core. J Biol Chem 279, 20836-20849. Tsai, H.Y., Chueh, L.L., Lin, C.N., Su, B.L., 2011, Clinicopathological findings and disease staging of feline infectious peritonitis: 51 cases from 2003 to 2009 in Taiwan. J Feline Med Surg 13, 74-80. Turville, S.G., Cameron, P.U., Handley, A., Lin, G., Pohlmann, S., Doms, R.W., Cunningham, A.L., 2002, Diversity of receptors binding HIV on dendritic cell subsets. Nat Immunol 3, 975-983. Van Hamme, E., Desmarets, L., Dewerchin, H.L., Nauwynck, H.J., 2011, Intriguing interplay between feline infectious peritonitis virus and its receptors during entry in primary feline monocytes. Virus Res 160, 32-39. Van Hamme, E., Dewerchin, H.L., Cornelissen, E., Nauwynck, H.J., 2007, Attachment and internalization of feline infectious peritonitis virus in feline blood monocytes and Crandell feline kidney cells. J Gen Virol 88, 2527-2532. van Kooyk, Y., Geijtenbeek, T.B., 2003, DC-SIGN: escape mechanism for pathogens. Nat Rev Immunol 3, 697-709. Vennema, H., 1999, Genetic drift and genetic shift during feline coronavirus evolution. Vet Microbiol 69, 139-141. Vennema, H., Godeke, G.J., Rossen, J.W., Voorhout, W.F., Horzinek, M.C., Opstelten, D.J., Rottier, P.J., 1996, Nucleocapsid-independent assembly of coronavirus-like particles by co-expression of viral envelope protein genes. EMBO J 15, 2020-2028. Vennema, H., Heijnen, L., Rottier, P.J., Horzinek, M.C., Spaan, W.J., 1992a, A novel 71 glycoprotein of feline infectious peritonitis coronavirus contains a KDEL-like endoplasmic reticulum retention signal. J Virol 66, 4951-4956. Vennema, H., Heijnen, L., Zijderveld, A., Horzinek, M.C., Spaan, W.J., 1990a, Intracellular transport of recombinant coronavirus spike proteins: implications for virus assembly. J Virol 64, 339-346. Vennema, H., Poland, A., Foley, J., Pedersen, N.C., 1998, Feline infectious peritonitis viruses arise by mutation from endemic feline enteric coronaviruses. Virology 243, 150-157. Vennema, H., Rossen, J.W., Wesseling, J., Horzinek, M.C., Rottier, P.J., 1992b, Genomic organization and expression of the 3' end of the canine and feline enteric coronaviruses. Virology 191, 134-140. Vennema, H., Rottier, P.J., Heijnen, L., Godeke, G.J., Horzinek, M.C., Spaan, W.J., 1990b, Biosynthesis and function of the coronavirus spike protein. Adv Exp Med Biol 276, 9-19. Weiss, R.C., Cox, N.R., Martinez, M.L., 1993, Evaluation of free or liposome-encapsulated ribavirin for antiviral therapy of experimentally induced feline infectious peritonitis. Res Vet Sci 55, 162-172. Weiss, R.C., Cox, N.R., Oostrom-Ram, T., 1990, Effect of interferon or Propionibacterium acnes on the course of experimentally induced feline infectious peritonitis in specific-pathogen-free and random-source cats. Am J Vet Res 51, 726-733. Weiss, R.C., Dodds, W.J., Scott, F.W., 1980, Disseminated intravascular coagulation in experimentally induced feline infectious peritonitis. Am J Vet Res 41, 663-671. Weiss, R.C., Oostrom-Ram, T., 1989, Inhibitory effects of ribavirin alone or combined 72 with human alpha interferon on feline infectious peritonitis virus replication in vitro. Vet Microbiol 20, 255-265. Weiss, R.C., Scott, F.W., 1981a, Antibody-mediated enhancement of disease in feline infectious peritonitis: comparisons with dengue hemorrhagic fever. Comp Immunol Microbiol Infect Dis 4, 175-189. Weiss, R.C., Scott, F.W., 1981b, Pathogenesis of feline infectious peritonitis: nature and development of viremia. Am J Vet Res 42, 382-390. Wise, A.G., Kiupel, M., Garner, M.M., Clark, A.K., Maes, R.K., 2010, Comparative sequence analysis of the distal one-third of the genomes of a systemic and an enteric ferret coronavirus. Virus Res 149, 42-50. Wolfe, L.G., Griesemer, R.A., 1966, Feline infectious peritonitis. Pathol Vet 3, 255-270. Wu, L., KewalRamani, V.N., 2006, Dendritic-cell interactions with HIV: infection and viral dissemination. Nat Rev Immunol 6, 859-868. Zhang, Y., Buckles, E., Whittaker, G.R., 2012, Expression of the C-type lectins DC-SIGN or L-SIGN alters host cell susceptibility for the avian coronavirus, infectious bronchitis virus. Vet Microbiol 157, 285-293. Zhou, T., Chen, Y., Hao, L., Zhang, Y., 2006, DC-SIGN and immunoregulation. Cell Mol Immunol 3, 279-283. Zook, B.C., King, N.W., Robinson, R.L., McCombs, H.L., 1968, Ultrastructural evidence for the viral etiology of feline infectious peritonitis. Pathol Vet 5, 91-95. | |
| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/15751 | - |
| dc.description.abstract | 中文摘要
貓冠狀病毒 (Feline coronavirus, FCoV) 廣泛存在於家貓及野生貓科動物，感 染雖大多僅出現輕微下痢或無臨床症狀，然有部分會發展為致死性之貓傳染性腹 膜炎 (Feline infectious peritonitis, FIP)。依血清型 FCoV 可被區分為第一與第二型， 兩型 FCoV 之感染皆可能發展成 FIP。為尋找有效抗病毒藥物與 FIP 致病機制探討 之需，本實驗自 2010 年至 2012 年間收集了 11 隻臨床上證實為 FIP 發病貓之新鮮 胸水及腹水，取其內之細胞與貓全胚胎細胞共同培養方式，其中一隻 10 月齡母貓 之腹水於繼代至第五代時，出現冠狀病毒感染所引起特異性細胞病變效應之多核 巨細胞，以抗 FCoV N protein 抗體對感染細胞進行免液螢光染色，結果可在多核 巨細胞質內發現強烈螢光訊號。此病毒經三次純化後，經核酸檢測確定為第二型 FCoV 並命名為 NTU204。以 Simplot 與 Bootscan 兩軟體分析 NTU204 之演化由來， 發現此病毒可能於基因體 13350nt 與 24800 nt 附近，透過第一型 FCoV 與犬或豬之 冠狀病毒經兩次重組而來，重組區域分別位於 RdRp 與 S 基因上。由於世界各地 FCoV 之感染，大多以第一型為主，相較於第二型此型病毒不易適應體外細胞培養 系統，因此分離工作相對困難。為提升第一型 FCoV 分離機率，本研究利用真核 表現載體將已被證實具提升 FCoV 感染能力之輔受器 fDC-SIGN 轉染至貓腎細胞， 將第二型 FCoV 病毒接種於此細胞時，發現在 1MOI 下表現 fDC-SIGN 之細胞確 實出現較高的病毒力價。證實此輔受器確實具提升病毒複製效應後，利用此細胞 嘗試進行第一型病毒之分離，則未能順利分離出來。 | zh_TW |
| dc.description.abstract | ABSTRACT
Feline coronavirus (FCoV) is widely distributed in domestic cats and wild felids. Most of the infections are asymptomatic or causing only mild diarrhea, however, some might result in fatal feline infectious peritonitis (FIP). FCoVs are divided into two distinct serotypes I and II that both can cause FIP. In order to isolate viruses for the study of antiviral agents and pathogenesis of FIP, fresh body effusion from a total of 11 FIP cats were collected from 2010 to 2012. Through co-cultivation of the cells derived from ascites of a 10-month-old cat with feline Fcwf-4 cell line to the fifth passages, a coronavirus specific cytopathic effect was observed and confirmed by immunofluorescent staining. After three times purification, sequencing and genotyping a local FCoV-II was confirmed (NTU204). Simplot and Bootscan analysis of NTU204 revealed two crossover events took place between FCoV-I and canine or pocine coronavirus. One of the possible recombination site is located in RdRp gene (around genome 13350 nt and the other is in S gene (around genome 24800 nt). FCoV-I is the more prevalent serotype currently in circulation; however, due to difficulties associated with in vitro cultivation only limited data can be found regarding its infection. In order to increase the isolation rate of FCoV-I, a known FCoV co-receptor (Feline dendritic cell-specific ICAM-3-grabbing nonintegrin, fDC-SIGN) was expressed in the susceptible feline cell line. When stable transfected cells expressing the expected fDC-SIGN were subjected to the infection of a Taiwanese FCoV-II isolate, viral titer was higher than the control cells at 1MOI. After confirming the co-receptor function of fDC-SIGN in the enhancement of viral replication, these stable clone cells were used to isolate FCoV-I. However, none of the isolate was able to be isolated. | en |
| dc.description.provenance | Made available in DSpace on 2021-06-07T17:51:21Z (GMT). No. of bitstreams: 1 ntu-101-R99629027-1.pdf: 2042586 bytes, checksum: a05993e4f23023e76339decb28be44d7 (MD5) Previous issue date: 2012 | en |
| dc.description.tableofcontents | 目錄
口試委員會審定書 ............................................................................................................i 中文摘要 .......................................................................................................................... ii ABSTRACT .................................................................................................................... iii 目錄 ..................................................................................................................................iv 表次 ..................................................................................................................................vi 圖次 ................................................................................................................................ vii 第一章、 文獻探討 .........................................................................................................1 第一節、 貓傳染性腹膜炎之歷史背景..................................................................1 第二節、 病毒分類..................................................................................................1 第三節、 基因體特性..............................................................................................2 第四節、 血清分型..................................................................................................5 第五節、 接受器 (Receptor) ..................................................................................5 第六節、 DC-SIGN .................................................................................................7 第七節、 流行病學與致病機制..............................................................................8 第八節、 臨床症狀與診斷....................................................................................10 第九節、 治療與預防............................................................................................12 第二章、 序言 ...............................................................................................................14 第三章、 材料與方法 ...................................................................................................16 第一節、 DC-SIGN 蛋白質之表現 ......................................................................16v 第二節、 FIP 自然感染貓隻之 FCoV 的分離與鑑定.........................................21 第三節、 冠狀病毒演化分析................................................................................26 第四章、 結果 ...............................................................................................................28 第一節、 DC-SIGN 蛋白之表現........................................................................28 第二節、 從自然感染 FCoV 病例之分離與鑑定.............................................30 第三節、 台灣貓冠狀病毒株重組點分析.........................................................31 第五章、 討論 ...............................................................................................................33 附表 .................................................................................................................................37 附圖 .................................................................................................................................42 參考文獻 .........................................................................................................................57vi 表次 表 1 貓小病毒與貓卡里西病毒特異性引子 ................................................................37 表 2 FCoV 重組點相關引子與各引子對增福基因片段位置 ......................................38 表 3 臨床 FCoV 陽性病例與檢體分型之結果 ............................................................39 表 4 臨床 FCoV 陽性檢體與細胞株共同培養並觀察 CPE 及檢測 FCoV 核酸結果40 表 5 FCoV 與其他物種之冠狀病毒 ..............................................................................41vii 圖次 圖 1 pCR R 2.1-TOPO R -fDC-SIGN 質體之選殖 ............................................................42 圖 2 fDC-SIGN 基因於真核表現載體之選殖...............................................................43 圖 3 fDC-SIGN 與真核表現載體 pCI-neo vector 接合後之核苷酸序列比對.............44 圖 4 fDC-SIGN 與真核表現載體 pCI-neo vector 接合後之胺基酸序列比對.............45 圖 5 人及貓隻血液 PBMC 來源之巨噬細胞之免疫螢光染色 ....................................46 圖 6 確認 fDC-SIGN 之免疫螢光染色.........................................................................47 圖 7 確認 fDC-SIGN 表現之西方墨點法分析.............................................................48 圖 8 CrFK-fDC-SIGN 之病毒力價測試 ........................................................................49 圖 9 貓冠狀病毒核酸之檢測 .......................................................................................50 圖 10 以 PCR 及 RT-nPCR 排除其他常見貓病毒之污染 ...........................................51 圖 11 貓冠狀病毒之確認 ..............................................................................................52 圖 12 比較本土第二型病毒株感染貓胚胎細胞 ..........................................................53 圖 13 NTU204 部分序列定序.......................................................................................54 圖 14 NTU204 重組區域之分析....................................................................................56 | |
| dc.language.iso | zh-TW | |
| dc.subject | 病毒重組 | zh_TW |
| dc.subject | 貓傳染性腹膜炎 | zh_TW |
| dc.subject | 貓冠狀病毒 | zh_TW |
| dc.subject | genetic recombination | en |
| dc.subject | feline coronavirus | en |
| dc.subject | feline infectious peritonitis | en |
| dc.title | 貓傳染性腹膜炎病毒之分離與基因分析 | zh_TW |
| dc.title | Isolation and Genetic Analysis of Feline Infectious Peritonitis Virus | en |
| dc.type | Thesis | |
| dc.date.schoolyear | 101-1 | |
| dc.description.degree | 碩士 | |
| dc.contributor.oralexamcommittee | 林昭男(Chao-nan Lin),徐維莉(Wei-Li Hsu),劉信孚(Hsin-Fu Liu),詹昆衛(Kun-Wei Chan),劉薏蓉(I-Jung Liu) | |
| dc.subject.keyword | 貓傳染性腹膜炎,貓冠狀病毒,病毒重組, | zh_TW |
| dc.subject.keyword | feline infectious peritonitis,feline coronavirus,genetic recombination, | en |
| dc.relation.page | 72 | |
| dc.rights.note | 未授權 | |
| dc.date.accepted | 2012-09-26 | |
| dc.contributor.author-college | 獸醫專業學院 | zh_TW |
| dc.contributor.author-dept | 獸醫學研究所 | zh_TW |
| 顯示於系所單位： | 獸醫學系 | |
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