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2014
轉運蛋白與CYP450酵素在藥物交互作用上所扮演角色之探討: 第一部分: CYP2C19與CYP3A4在氫離子幫浦抑制劑與抗凝血藥物(clopidogrel與prasugrel)之藥物交互作用上所扮演角色之探討 第二部分: P-glycoprotein與CYP450酵素對於紅麴中lovastatin之生體可用率影響之探討 第三部分: 關節炎對於轉運蛋白與CYP450酵素之表現與對於leflunomide、simvastatin與rosuvastatin藥動性質影響之探討
Roles of transporters and CYP450 enzymes on drug interaction: Part I: CYP2C19 and CYP3A4-mediated drug-drug interaction between PPIs and anticoagulant agents (clopidogrel and prasugrel). Part II: Roles of P-glycoprotein and CYP450 enzymes on the bioavailability of lovastatin in red yeast rice. Part III: The Effect of arthritis on the expression of transporters and CYP450 enzymes and its implication to the pharmacokinetics of leflunomide, simvastatin, and rosuvastatin.
Chia-Hao Chen; 陳佳壕
藥學研究所
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cyp450 enzymes
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cyp450 enzymes,transporters
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cyp450 enzymes,transporters,drug ...
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cyp450 enzymes,transporters,drug ...
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cyp酵素
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cyp酵素,轉運蛋白
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cyp酵素,轉運蛋白,藥物交互作用,紅麴
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