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| DC 欄位 | 值 | 語言 |
|---|---|---|
| dc.contributor.advisor | 王兆麟 | zh_TW |
| dc.contributor.advisor | Jaw-Lin Wang | en |
| dc.contributor.author | 張家誌 | zh_TW |
| dc.contributor.author | Chia-Chih Chang | en |
| dc.date.accessioned | 2026-08-26T16:34:02Z | - |
| dc.date.available | 2026-08-27 | - |
| dc.date.copyright | 2026-08-26 | - |
| dc.date.issued | 2026 | - |
| dc.date.submitted | 2026-07-22 00:00:00 | - |
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| dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/104435 | - |
| dc.description.abstract | 骨組織本身具有壓電特性，當骨骼受到力學刺激時可產生局部電位變化，進而活化細胞訊號傳遞並促進骨修復。基於此，本研究旨在於Ti-6Al-4V骨科植入物表面製備具壓電特性之BaTiO3（BTO）塗層，藉由材料本身之壓電效應，建立有利於骨癒合之電生理微環境。研究首先以陽極處理於 Ti6Al4V 基板表面形成TiO2前驅層，後續利用水熱法於180°C下以Ba(OH)2與KOH反應液原位成長BTO塗層，並進一步結合退火與極化處理，以調控材料之晶相結構與偶極排列，提升其壓電性能。
結果顯示，不同陽極處理厚度中，以T2M組別可形成較適合BTO成長之TiO2前驅層；水熱反應條件方面，0.5M Ba(OH)2與1.5M KOH 可使BTO塗層形成更為緻密且均勻之珊瑚狀結構，並獲得較佳之結晶表現。退火部分則發現600°C可在不明顯損傷Ti-6Al-4V基材之情況下，有效提升BTO之四方相特徵與局部壓電響應，其中PFM量測顯示其d33值可達約98 pm/V。相較之下，800°C以上退火則會造成塗層剝落與基材氧化，降低材料完整性。至於極化處理，雖然電暈極化與熱電暈極化後之塗層形貌與晶相仍可維持，但在本研究所採用之條件下，壓電響應未獲顯著提升，顯示後續仍需進一步優化極化參數。 綜合而言，本研究成功透過水熱法於Ti-6Al-4V基板上製備具壓電潛力之BTO塗層，並建立陽極處理、水熱濃度、退火溫度與極化條件之製程關聯。此結果不僅提供一套可應用於骨科植入物之壓電塗層製備策略，亦為未來開發低溫、簡化且具生醫應用潛力之功能性陶瓷塗層奠定基礎。 | zh_TW |
| dc.description.abstract | Bone exhibits intrinsic piezoelectricity, and mechanical loading can generate localized electrical potentials that promote cellular signaling and bone repair. Based on this concept, this study aimed to fabricate a piezoelectric BaTiO3 (BTO) coating on Ti-6Al-4V orthopedic implants in order to create a bioelectrical microenvironment favorable for bone healing. A TiO2 precursor layer was first formed on the Ti-6Al-4V substrate by anodization. BTO was then grown in situ by hydrothermal synthesis at 180°C using an aqueous Ba(OH)2/KOH solution, followed by annealing and polarization to regulate crystal structure and dipole alignment and thereby improve piezoelectric performance.
The results showed that the T2M anodization condition produced the most suitable TiO2 precursor layer for BTO growth. For hydrothermal synthesis, 0.5 M Ba(OH)2 and 1.5 M KOH yielded a denser and more uniform coral-like BTO coating with improved crystallinity. Among the annealing conditions investigated, 600°C provided the best overall performance, enhancing the tetragonal phase characteristics and local piezoelectric response of BTO without noticeable damage to the Ti-6Al-4V substrate; PFM analysis showed a maximum d33 value of approximately 98 pm/V. In contrast, annealing above 800°C caused coating delamination and substrate oxidation, leading to degraded structural integrity. Although corona poling and thermo-corona poling preserved the coating morphology and phase structure, no significant improvement in piezoelectric response was observed under the conditions used in this study, indicating that further optimization of the poling parameters is required. In summary, this study demonstrates the successful fabrication of a BTO coating with piezoelectric potential on Ti-6Al-4V substrates by hydrothermal synthesis and establishes the relationships among anodization, hydrothermal solution concentration, annealing temperature, and polarization conditions. These findings provide a practical strategy for piezoelectric coatings on orthopedic implants and lay the foundation for future development of low-temperature, simplified, and bio-functional ceramic coatings for biomedical applications. | en |
| dc.description.provenance | Submitted by admin ntu (admin@lib.ntu.edu.tw) on 2026-08-26T16:34:02Z No. of bitstreams: 0 | en |
| dc.description.provenance | Made available in DSpace on 2026-08-26T16:34:02Z (GMT). No. of bitstreams: 0 | en |
| dc.description.tableofcontents | 口試委員審定書 I
致謝 II 摘要 III Abstract IV 目次 VI 圖次 IX 第一章 緒論 1 1.1研究背景與臨床需求 1 1.2壓電效應與骨癒合的生物學基礎 3 1.3壓電材料簡介與其在骨科植入物的優劣勢分析 6 1.3.1正壓電效應與逆壓電效應之間的公式轉換 6 1.3.2壓電材料簡介 7 1.3.3壓電材料在骨科植入物的優劣勢分析 8 1.4研究製程挑戰與研究目的 10 第二章 鈦酸鋇製程文獻探討 13 2.1鈦酸鋇簡介 13 2.1.1 BTO的基本組成與晶體結構 13 2.1.2 BTO的相變行為與壓電特性來源 14 2.1.3 BTO作為生醫植入物塗層材料的潛力 15 2.2 BTO特性之材料分析方式 17 2.2.1拉曼散射光譜分析(Raman Spectroscopy) 17 2.2.2 X光繞射(X-ray Diffraction, XRD) 18 2.2.3壓電響應力顯微鏡(Piezo-response Force Microscopy, PFM) 20 2.3 BTO的製程及其挑戰 22 2.3.1高溫製程 (APS/SPS/PLD) 23 2.3.2低溫製程(水熱合成, Hydrothermal) 24 2.4增強BTO壓電特性的後處理 26 2.4.1退火(Annealing) 26 2.4.2極化(Polarization) 28 第三章 材料與方法 30 3.1研究架構與實驗設計 30 3.2 BTO塗層製備 31 3.2.1試片前處理(Pre-Processing) 32 3.2.2陽極處理(Anodization) 32 3.2.3水熱反應(Hydrothermal) 33 3.2.4退火(Annealing) 34 3.2.5極化(Polarization) 35 3.3 BTO材料試驗分析方式 37 3.3.1 SEM/EDX 38 3.3.2 Raman Spectroscopy 38 3.3.3 XRD 39 3.3.4 PFM 40 第四章 結果與討論 42 4.1陽極處理對BTO塗層之影響 42 4.2水熱反應對BTO塗層之影響 51 4.2.1 Ba(OH)2濃度之影響 51 4.2.2 KOH濃度之影響 56 4.3退火對提升BTO壓電特性之影響 59 4.3.1退火溫度對BTO塗層表面形貌與成分之影響 60 4.3.2退火溫度對BTO塗層四方相之影響 68 4.3.3退火溫度對BTO塗層壓電特性之影響 74 4.4極化對提升BTO塗層壓電特性之影響 83 4.5討論 91 第五章 總結與未來展望 94 5.1總結 94 5.2未來展望 95 參考文獻 98 | - |
| dc.language.iso | zh_TW | - |
| dc.subject | 鈦酸鋇 | - |
| dc.subject | 壓電塗層 | - |
| dc.subject | Ti-6Al-4V | - |
| dc.subject | 水熱反應 | - |
| dc.subject | 退火 | - |
| dc.subject | 極化 | - |
| dc.subject | 骨科植入物 | - |
| dc.subject | Barium Titanate | - |
| dc.subject | Piezoelectric Coating | - |
| dc.subject | Ti-6Al-4V | - |
| dc.subject | Hydrothermal synthesis | - |
| dc.subject | Annealing | - |
| dc.subject | Polarization | - |
| dc.subject | Orthopedic Implant | - |
| dc.title | 促進骨癒合之水熱合成壓電 BaTiO3 塗層技術開發 | zh_TW |
| dc.title | Development of Hydrothermal Piezoelectric BaTiO3 Coating Technology for Promoting Bone Healing | en |
| dc.type | Thesis | - |
| dc.date.schoolyear | 114-2 | - |
| dc.description.degree | 碩士 | - |
| dc.contributor.oralexamcommittee | 張志豪;黃育熙;陳文翔;蔡佩宜 | zh_TW |
| dc.contributor.oralexamcommittee | Chih-Hao Chang;Yu-Hsi Huang;Wen-Shiang Chen;Pei-Yi Tsai | en |
| dc.subject.keyword | 鈦酸鋇; 壓電塗層; Ti-6Al-4V; 水熱反應; 退火; 極化; 骨科植入物 | zh_TW |
| dc.subject.keyword | Barium Titanate; Piezoelectric Coating; Ti-6Al-4V; Hydrothermal synthesis; Annealing; Polarization; Orthopedic Implant | en |
| dc.relation.page | 105 | - |
| dc.identifier.doi | 10.6342/NTU202602293 | - |
| dc.rights.note | 同意授權(限校園內公開) | - |
| dc.date.accepted | 2026-07-23 | - |
| dc.contributor.author-college | 工學院 | - |
| dc.contributor.author-dept | 醫學工程學系 | - |
| dc.date.embargo-lift | 2031-07-21 | - |
| 顯示於系所單位： | 醫學工程學研究所 | |
文件中的檔案：
| 檔案 | 大小 | 格式 | |
|---|---|---|---|
| ntu-114-2.pdf 未授權公開取用 | 6.9 MB | Adobe PDF | 檢視/開啟 |
系統中的文件，除了特別指名其著作權條款之外，均受到著作權保護，並且保留所有的權利。