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完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.advisor | 李永凌 | |
dc.contributor.author | Jer-Min Chen | en |
dc.contributor.author | 陳哲民 | zh_TW |
dc.date.accessioned | 2021-06-15T04:57:28Z | - |
dc.date.available | 2012-09-09 | |
dc.date.copyright | 2010-09-09 | |
dc.date.issued | 2010 | |
dc.date.submitted | 2010-07-29 | |
dc.identifier.citation | 1.Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31(1):143-78.
2.Eder W, Ege MJ, von Mutius E. The asthma epidemic. N Engl J Med 2006;355(21):2226-35. 3.Downs SH, Marks GB, Sporik R, Belosouva EG, Car NG, Peat JK. Continued increase in the prevalence of asthma and atopy. Arch Dis Child 2001;84(1):20-23. 4.Lee YL, Hwang BF, Lin YC, Guo YL. Time trend of asthma prevalence among school children in Taiwan: ISAAC phase I and III surveys. Pediatr Allergy Immunol 2007;18(3):188-95. 5.Braman SS. The global burden of asthma. Chest 2006;130(1 Suppl):4S-12S. 6.Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004;59(5):469-78. 7.Ober C. Perspectives on the past decade of asthma genetics. J Allergy Clin Immunol 2005;116(2):274-8. 8.Barker JS, Starmer WT. Environmental effects and the genetics of oviposition site preference for natural yeast substrates in Drosophila buzzatii. Hereditas 1999;130(2):145-75. 9.von Mutius E. Gene-environment interactions in asthma. J Allergy Clin Immunol 2009;123(1):3-11; quiz 12-3. 10.Szekely E, Farkas E. Pediatric Bronchology. Baltimore;University Park Press. 11.Serpell J. Beneficial effects of pet ownership on some aspects of human health and behaviour. J R Soc Med 1991;84(12):717-20. 12.Platt SD, Martin CJ, Hunt SM, Lewis CW. Damp housing, mould growth, and symptomatic health state. BMJ 1989;298(6689):1673-8. 13.李蘭. 台灣地區成年人之吸菸率與吸菸行為:八十八年度之全國性調查. 台灣公共衛生雜誌 1999;19(6). 14.Gilliland FD, Berhane K, Islam T, Wenten M, Rappaport E, Avol E, et al. Environmental tobacco smoke and absenteeism related to respiratory illness in schoolchildren. Am J Epidemiol 2003;157(10):861-9. 15.周思源. 台灣地區在校青少年吸菸、喝酒及嚼食檳榔與藥物使用之盛行率. 中台灣醫學科學雜誌 2005;11:177. 16.Holgate ST. Pathogenesis of asthma. Clin Exp Allergy 2008;38(6):872-97. 17.Larche M, Robinson DS, Kay AB. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003;111(3):450-63; quiz 464. 18.McConnell R, Berhane K, Gilliland F, Islam T, Gauderman WJ, London SJ, et al. Indoor risk factors for asthma in a prospective study of adolescents. Epidemiology 2002;13(3):288-95. 19.Perzanowski MS, Ronmark E, Platts-Mills TA, Lundback B. Effect of cat and dog ownership on sensitization and development of asthma among preteenage children. Am J Respir Crit Care Med 2002;166(5):696-702. 20.Linneberg A, Nielsen NH, Madsen F, Frolund L, Dirksen A, Jorgensen T. Pets in the home and the development of pet allergy in adulthood. The Copenhagen Allergy Study. Allergy 2003;58(1):21-6. 21.de Meer G, Toelle BG, Ng K, Tovey E, Marks GB. Presence and timing of cat ownership by age 18 and the effect on atopy and asthma at age 28. J Allergy Clin Immunol 2004;113(3):433-8. 22.Litonjua AA, Milton DK, Celedon JC, Ryan L, Weiss ST, Gold DR. A longitudinal analysis of wheezing in young children: the independent effects of early life exposure to house dust endotoxin, allergens, and pets. J Allergy Clin Immunol 2002;110(5):736-42. 23.Dong GH, Ma YN, Ding HL, Jin J, Cao Y, Zhao YD, et al. Pets keeping in home, parental atopy, asthma, and asthma-related symptoms in 12,910 elementary school children from northeast China. Indoor Air 2009;19(2):166-73. 24.Yang CY, Chiu JF, Cheng MF, Lin MC. Effects of indoor environmental factors on respiratory health of children in a subtropical climate. Environ Res 1997;75(1):49-55. 25.Ronmark E, Perzanowski M, Platts-Mills T, Lundback B. Incidence rates and risk factors for asthma among school children: a 2-year follow-up report from the obstructive lung disease in Northern Sweden (OLIN) studies. Respir Med 2002;96(12):1006-13. 26.Jaakkola JJ, Hwang BF, Jaakkola N. Home dampness and molds, parental atopy, and asthma in childhood: a six-year population-based cohort study. Environ Health Perspect 2005;113(3):357-61. 27.Simoni M, Lombardi E, Berti G, Rusconi F, La Grutta S, Piffer S, et al. Mould/dampness exposure at home is associated with respiratory disorders in Italian children and adolescents: the SIDRIA-2 Study. Occup Environ Med 2005;62(9):616-22. 28.Yang CY, Chiu JF, Chiu HF, Kao WY. Damp housing conditions and respiratory symptoms in primary school children. Pediatr Pulmonol 1997;24(2):73-7. 29.Mommers M, Jongmans-Liedekerken AW, Derkx R, Dott W, Mertens P, van Schayck CP, et al. Indoor environment and respiratory symptoms in children living in the Dutch-German borderland. Int J Hyg Environ Health 2005;208(5):373-81. 30.Saetta M, Turato G, Maestrelli P, Mapp CE, Fabbri LM. Cellular and structural bases of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001;163(6):1304-9. 31.Jeffery PK. Structural and inflammatory changes in COPD: a comparison with asthma. Thorax 1998;53(2):129-36. 32.Roth MD, Arora A, Barsky SH, Kleerup EC, Simmons M, Tashkin DP. Airway inflammation in young marijuana and tobacco smokers. Am J Respir Crit Care Med 1998;157(3 Pt 1):928-37. 33.Hunninghake GW, Crystal RG. Cigarette smoking and lung destruction. Accumulation of neutrophils in the lungs of cigarette smokers. Am Rev Respir Dis 1983;128(5):833-8. 34.Thompson AB, Daughton D, Robbins RA, Ghafouri MA, Oehlerking M, Rennard SI. Intraluminal airway inflammation in chronic bronchitis. Characterization and correlation with clinical parameters. Am Rev Respir Dis 1989;140(6):1527-37. 35.Costabel U, Guzman J. Effect of smoking on bronchoalveolar lavage constituents. Eur Respir J 1992;5(7):776-9. 36.Lams BE, Sousa AR, Rees PJ, Lee TH. Immunopathology of the small-airway submucosa in smokers with and without chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;158(5 Pt 1):1518-23. 37.Seymour BW, Pinkerton KE, Friebertshauser KE, Coffman RL, Gershwin LJ. Second-hand smoke is an adjuvant for T helper-2 responses in a murine model of allergy. J Immunol 1997;159(12):6169-75. 38.Seymour BW, Schelegle ES, Pinkerton KE, Friebertshauser KE, Peake JL, Kurup VP, et al. Second-hand smoke increases bronchial hyperreactivity and eosinophilia in a murine model of allergic aspergillosis. Clin Dev Immunol 2003;10(1):35-42. 39.Wu ZX, Morton RF, Lee LY. Role of tachykinins in ozone-induced airway hyperresponsiveness to cigarette smoke in guinea pigs. J Appl Physiol 1997;83(3):958-65. 40.Lei YH, Barnes PJ, Rogers DF. Mechanisms and modulation of airway plasma exudation after direct inhalation of cigarette smoke. Am J Respir Crit Care Med 1995;151(6):1752-62. 41.Floreani AA, Rennard SI. The role of cigarette smoke in the pathogenesis of asthma and as a trigger for acute symptoms. Curr Opin Pulm Med 1999;5(1):38-46. 42.Henderson WR, Jr. Role of leukotrienes in asthma. Ann Allergy 1994;72(3):272-8. 43.O'Byrne PM, Israel E, Drazen JM. Antileukotrienes in the treatment of asthma. Ann Intern Med 1997;127(6):472-80. 44.Weiland SK, Bjorksten B, Brunekreef B, Cookson WO, von Mutius E, Strachan DP. Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II): rationale and methods. Eur Respir J 2004;24(3):406-12. 45.Burney P, Chinn S. Developing a new questionnaire for measuring the prevalence and distribution of asthma. Chest 1987;91(6 Suppl):79S-83S. 46.Genuneit J, Weinmayr G, Radon K, Dressel H, Windstetter D, Rzehak P, et al. Smoking and the incidence of asthma during adolescence: results of a large cohort study in Germany. Thorax 2006;61(7):572-8. 47.Withers NJ, Low L, Holgate ST, Clough JB. The natural history of respiratory symptoms in a cohort of adolescents. Am J Respir Crit Care Med 1998;158(2):352-7. 48.Gilliland FD, Islam T, Berhane K, Gauderman WJ, McConnell R, Avol E, et al. Regular smoking and asthma incidence in adolescents. Am J Respir Crit Care Med 2006;174(10):1094-100. 49.McConnell R, Berhane K, Gilliland F, London SJ, Vora H, Avol E, et al. Air pollution and bronchitic symptoms in Southern California children with asthma. Environ Health Perspect 1999;107(9):757-60. 50.Peters JM, Avol E, Navidi W, London SJ, Gauderman WJ, Lurmann F, et al. A study of twelve Southern California communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. Am J Respir Crit Care Med 1999;159(3):760-7. 51.Huberman M, Langholz B. Application of the missing-indicator method in matched case-control studies with incomplete data. Am J Epidemiol 1999;150(12):1340-5. 52.McNutt LA, Wu C, Xue X, Hafner JP. Estimating the relative risk in cohort studies and clinical trials of common outcomes. Am J Epidemiol 2003;157(10):940-3. 53.Callas PW, Pastides H, Hosmer DW. Empirical comparisons of proportional hazards, poisson, and logistic regression modeling of occupational cohort data. Am J Ind Med 1998;33(1):33-47. 54.Bland JM, Altman DG. Multiple significance tests: the Bonferroni method. BMJ 1995;310(6973):170. 55.Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007;39(2):175-91. 56.Coughlin SS, Benichou J, Weed DL. Attributable risk estimation in case-control studies. Epidemiol Rev 1994;16(1):51-64. 57.de Marco R, Locatelli F, Sunyer J, Burney P. Differences in incidence of reported asthma related to age in men and women. A retrospective analysis of the data of the European Respiratory Health Survey. Am J Respir Crit Care Med 2000;162(1):68-74. 58.De Marco R, Locatelli F, Cerveri I, Bugiani M, Marinoni A, Giammanco G. Incidence and remission of asthma: a retrospective study on the natural history of asthma in Italy. J Allergy Clin Immunol 2002;110(2):228-35. 59.Johansson SG, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, et al. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy 2001;56(9):813-24. 60.Gereda JE, Leung DY, Thatayatikom A, Streib JE, Price MR, Klinnert MD, et al. Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma. Lancet 2000;355(9216):1680-3. 61.Gereda JE, Klinnert MD, Price MR, Leung DY, Liu AH. Metropolitan home living conditions associated with indoor endotoxin levels. J Allergy Clin Immunol 2001;107(5):790-6. 62.Chen CM, Mielck A, Fahlbusch B, Bischof W, Herbarth O, Borte M, et al. Social factors, allergen, endotoxin, and dust mass in mattress. Indoor Air 2007;17(5):384-93. 63.Liccardi G, Cazzola M, D'Amato M, D'Amato G. Pets and cockroaches: two increasing causes of respiratory allergy in indoor environments. Characteristics of airways sensitization and prevention strategies. Respir Med 2000;94(11):1109-18. 64.Custovic A, Green R, Taggart SC, Smith A, Pickering CA, Chapman MD, et al. Domestic allergens in public places. II: Dog (Can f1) and cockroach (Bla g 2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings. Clin Exp Allergy 1996;26(11):1246-52. 65.Heinrich J, Bedada GB, Zock JP, Chinn S, Norback D, Olivieri M, et al. Cat allergen level: its determinants and relationship to specific IgE to cat across European centers. J Allergy Clin Immunol 2006;118(3):674-81. 66.Eller E, Roll S, Chen CM, Herbarth O, Wichmann HE, von Berg A, et al. Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative. Allergy 2008;63(11):1491-8. 67.Norback D, Bjornsson E, Janson C, Palmgren U, Boman G. Current asthma and biochemical signs of inflammation in relation to building dampness in dwellings. Int J Tuberc Lung Dis 1999;3(5):368-76. 68.Bornehag CG, Blomquist G, Gyntelberg F, Jarvholm B, Malmberg P, Nordvall L, et al. Dampness in buildings and health. Nordic interdisciplinary review of the scientific evidence on associations between exposure to 'dampness' in buildings and health effects (NORDDAMP). Indoor Air 2001;11(2):72-86. 69.Agudo A, Bardagi S, Romero PV, Gonzalez CA. Exercise-induced airways narrowing and exposure to environmental tobacco smoke in schoolchildren. Am J Epidemiol 1994;140(5):409-17. 70.Schwartz J, Timonen KL, Pekkanen J. Respiratory effects of environmental tobacco smoke in a panel study of asthmatic and symptomatic children. Am J Respir Crit Care Med 2000;161(3 Pt 1):802-6. 71.Burr ML. Diagnosing asthma by questionnaire in epidemiological surveys. Clin Exp Allergy 1992;22(5):509-10. 72.Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC). Eur Respir J 1998;12(2):315-35. 73.Burney PG, Laitinen LA, Perdrizet S, Huckauf H, Tattersfield AE, Chinn S, et al. Validity and repeatability of the IUATLD (1984) Bronchial Symptoms Questionnaire: an international comparison. Eur Respir J 1989;2(10):940-5. 74.Nafstad P, Oie L, Mehl R, Gaarder PI, Lodrup-Carlsen KC, Botten G, et al. Residential dampness problems and symptoms and signs of bronchial obstruction in young Norwegian children. Am J Respir Crit Care Med 1998;157(2):410-4. 75.Almqvist C, Egmar AC, van Hage-Hamsten M, Berglind N, Pershagen G, Nordvall SL, et al. Heredity, pet ownership, and confounding control in a population-based birth cohort. J Allergy Clin Immunol 2003;111(4):800-6. | |
dc.identifier.uri | http://tdr.lib.ntu.edu.tw/jspui/handle/123456789/46193 | - |
dc.description.abstract | 背景:氣喘是孩童和青少年時期最常見的慢性呼吸道發炎性疾病,盛行率在世界多數國家包括台灣仍呈現一個上升的趨勢。氣喘發作時易在夜間或清晨反覆出現呼吸喘鳴、呼吸困難、胸悶及咳嗽等症狀,有時與支氣管炎的臨床表現常不易區別,但兩者皆會影響青少年的生活及學習,帶給個人、家庭及社會重大的衝擊及損耗。氣喘及支氣管炎的致病機轉相當複雜,基本上可分為宿主及環境因子兩大類,環境因素包含室內過敏原、感染及菸害等,過去針對室內環境因子對於呼吸道健康的相關性研究多來自橫斷性或病例對照研究,且針對青少年族群也相對較少。
研究方法:本研究設計為追蹤研究,我們於2007年在台灣隨機選取14個不同社區內國中7、8、9年級的學生(12-14歲),以問卷收集個人及家庭健康狀況和室內環境因子及菸害暴露資料,當年度完成問卷者有5091位學生,回答率為87.7%。在2009年追蹤研究時我們排除了2007年為8、9年級學生共957位學生,對當時為7年級4134位青少年進行追蹤問卷研究。在結果定義方面,如2007年回答無呼吸道症狀而在2009年回答有的青少年,即視為一個呼吸道症狀新發生個案;暴露及相關干擾因子資料則以基礎問卷獲得。室內環境因子與菸害對於呼吸道疾病及症狀發生藉由布阿松迴歸(Poisson regression)模型來檢視其相關性,對於研究設計上的多重檢定影響,則以Bonferroni法進行校正。 研究結果:2009年追蹤到的總人數為3909人(追蹤率94.6%)。呼吸道症狀的兩年累積發生率介於1.4∼18.5%。經過校正年齡、性別、父母的氣喘及過敏病史,母親在懷孕過程中有無吸菸、青少年的身體質量指數及社區之後,青少年本身吸菸會增加運動中或運動後呼吸道喘鳴(RR=1.45; 95% CI=1.01-2.08)、慢性咳嗽(RR=1.77; 95% CI=1.04-3.00)及沒感冒時就胸腔卡痰或咳痰危險性( RR=1.65; 95% CI= 1.03-2.66),而且青少年的吸菸量及菸齡對於慢性咳嗽及沒感冒時就胸腔卡痰或咳痰的危險性呈現劑量效應關係。二手菸暴露會造成慢性咳嗽發生危險性增加,不論是由終生暴露(RR=1.40; 95% CI=1.04-1.88)或目前仍有暴露來看皆有顯著的相關性(RR=1.35; 95% CI=1.01-1.81),且接觸二手菸時間長短與慢性咳嗽的發生危險性上呈現劑量效應。青少年已有氣喘或喘鳴疾病史並接觸二手菸,不論是終生暴露或是目前仍有暴露,會顯著增加沒感冒時就胸腔卡痰或咳痰發生的危險性,且具有交互作用(p for interaction=0.05; 0.03)。在本研究中,室內家中飼養寵物及潮濕因子對於呼吸道疾病的發生並無顯著的統計相關。 結論:本研究發現在台灣青少年中,自己吸菸會增加運動中或運動後呼吸道喘鳴及支氣管症狀發生的危險性;在家中暴露於二手菸則與支氣管症狀發生具有正相關。 | zh_TW |
dc.description.abstract | Background: The risk of asthma and respiratory symptoms associated with indoor environmental risk factors and tobacco smoke has been examined in both cross-sectional and prospective studies of younger children. However, few studies have investigated the role of the same exposures on respiratory symptoms onset during adolescence. We examined the association of indoor environmental factors and tobacco smoke with the subsequent development of asthma and respiratory symptoms among cohorts of Taiwanese adolescents.
Methods: Risk factors for the development of asthma, wheezing disorders and bronchitic symptoms were examined in Taiwan Children Health Study (TCHS) of 3909 7th grade adolescents from 14 different communities in Taiwan at 2007 entry into the study, who were followed for up to 2 years. Newly diagnosed cases of respiratory conditions were identified by follow-up questionnaire in 2009. The risk associated with indoor risk factors and tobacco smoke assessed by questionnaire at entry into the study was examined using Poisson regression model with Bonferroni adjustment for multiple comparison. Results: The cumulative incidences of asthma, wheezing disorders and bronchitic symptoms are between 1.4~18.5%. Tobacco smoke was associated with increased risks of developing exercise induced wheeze and bronchitic symptoms. Adolescents who reported smoking had a relative risk (RR) of 1.45(95% confidence interval [CI]=1.01-2.08) for new-onset exercise induced wheeze compared with nonsmokers . The effects of current (RR=1.35; 95% CI=1.01-1.81) and lifetime (RR=1.40; 95% CI=1.04-1.88) secondhand smoke (SHS) were associated with increased risk on chronic cough. An increased risk on developing chronic cough (RR=1.77; 95% CI=1.04-3.00) and phlegm without having cold (RR=1.65; 95% CI=1.03-2.66) with active smoking were noted. The interaction of SHS with asthma or wheeze history of participants at baseline was significant on developing bronchitic symptoms. In our study, there was no significant association between raising furry pets at home, indoor dampness and respiratory symptoms development. Conclusion: We conclude that tobacco smoke is a risk factor for new-onset exercise induced wheeze and bronchitic symptoms in Taiwanese adolescents. | en |
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dc.description.tableofcontents | 口試委員會審定書 II
致謝 II 中文摘要 III Abstract V 目 錄 VII 圖目錄 X 表目錄 XI 第一章 緒論 1 1.1 研究背景及動機 1 1.2 研究目的及假說 3 第二章 文獻回顧 7 2.1 室內過敏原與氣喘及呼吸道症狀 7 2.1.1 室內過敏原致病機轉 7 2.1.2 有毛寵物及地毯與氣喘及呼吸道症狀發生的相關性研究 7 2.1.3 室內潮濕因子與氣喘及呼吸道症狀發生的相關性研究 9 2.2 吸菸及二手菸與氣喘及呼吸道疾病 10 2.2.1 吸菸與二手菸致病機轉 10 2.2.2 吸菸與氣喘及呼吸道症狀發生的相關性研究 11 第三章 研究材料及方法 24 3.1 研究架構 24 3.2 研究對象 24 3.3 問卷設計 25 3.3.1 暴露的定義 25 3.3.2 結果的定義 27 3.4 干擾因子 28 3.5 統計方法 28 第四章 結果 32 4.1 世代研究族群基本資料 32 4.2 室內環境因子的盛行率 33 4.3 氣喘及呼吸道症狀累積發生率 34 4.4 危險因子迴歸分析結果 35 4.4.1 室內環境因子與氣喘、喘鳴疾患(wheezing disorders)發生的相關性 35 4.4.1.1 室內寵物及地毯 35 4.4.1.2 室內潮濕因子 35 4.4.1.3 吸菸及二手菸暴露 35 4.4.1.4 支氣管症狀病史與二手菸對於喘鳴疾病發生之交互作用 36 4.4.2 室內環境因子與支氣管症狀(bronchitic symptoms)發生的相關性 36 4.4.2.1 室內寵物及地毯 36 4.4.2.2 室內潮濕因子 37 4.4.2.3 吸菸及二手菸 37 4.4.2.4 氣喘或喘鳴病史與二手菸對於支氣管症狀發生之交互作用 38 第五章 討論 51 5.1 研究發現與過去文獻之比較 51 5.1.1 台灣及各國氣喘及呼吸道喘鳴發生率 51 5.1.2 家中飼養有毛寵物與氣喘及呼吸道症狀相關性 51 5.1.3 家中潮濕因子與氣喘及呼吸道症狀相關性 52 5.1.4 吸菸、二手菸與氣喘及呼吸道症狀相關性 53 5.2 研究優點及發現 55 5.3 研究限制 56 5.4 未來方向 57 第六章 結論 58 參考資料 59 附錄1 台灣兒童健康研究問卷 65 附錄2 衛生署兒童及青少年身體質量指數表 73 附錄3 研究檢定力表 74 | |
dc.language.iso | zh-TW | |
dc.title | 居家室內環境因子對於青少年呼吸道症狀發生之研究 | zh_TW |
dc.title | Household Environmental Factors for Incidence of Respiratory Symptoms in Adolescents | en |
dc.type | Thesis | |
dc.date.schoolyear | 98-2 | |
dc.description.degree | 碩士 | |
dc.contributor.oralexamcommittee | 季瑋珠,江伯倫,簡國龍,黃彬芳 | |
dc.subject.keyword | 呼吸道症狀,發生率,室內環境,寵物,潮濕,吸菸, | zh_TW |
dc.subject.keyword | respiratory symptoms,incidence,indoor environment,pet,dampness,smoking, | en |
dc.relation.page | 74 | |
dc.rights.note | 有償授權 | |
dc.date.accepted | 2010-07-29 | |
dc.contributor.author-college | 公共衛生學院 | zh_TW |
dc.contributor.author-dept | 預防醫學研究所 | zh_TW |
顯示於系所單位: | 流行病學與預防醫學研究所 |
文件中的檔案:
檔案 | 大小 | 格式 | |
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ntu-99-1.pdf 目前未授權公開取用 | 4.99 MB | Adobe PDF |
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